Nandrolone phenylpropionate

Product Details

Purpose 1
Used for the treatment of developmental disorders, nutritional disorders, and consumptive diseases.
Common hormones
Norolone propionate is a commonly used hormone that promotes protein synthesis and metabolism, also known as Nanolone propionate, androsterone propionate, nortestosterone propionate, doxorubicin, and doxorubicin. It is prepared by esterification of 19-demethyltestosterone with phenylpropionyl chloride. Its dosage form is an oily injection, administered through intramuscular injection. It can promote protein synthesis and accumulate calcium, phosphorus, and potassium, used for severe osteoporosis, premature infants, growth and development delay, dwarfism, severe malnutrition, etc; It can also be used for breast cancer, functional uterine bleeding, uterine fibroids, etc. that are not suitable for surgery. However, this product may have a slight masculinization effect; Not suitable for long-term use; Prostate cancer, hypertension, and pregnant women should avoid using it; Be cautious when using with poor heart, liver, and kidney function.
This information is edited and organized by Xiangyun from ChemicalBook.
Physical and chemical properties
White or milky white crystalline powder with a special odor. Melting point 95-99 ℃, relative density 1.14g/cm3[ α] D20+48~+51 ℃ (dioxane). Soluble in ethanol, tea oil, slightly soluble in vegetable oil; Almost insoluble in water.
pharmacological action 
The protein assimilation effect of this product is 12 times that of testosterone propionate, while the androgen activity is smaller, 1.5 times that of the latter. It can promote protein synthesis and inhibit protein heterogenesis, and has effects such as calcium and phosphorus deposition and promoting bone tissue growth. Its intramuscular injection effect can last for 1-2 weeks.
Pharmacokinetics
Metabolism: Hormones are excreted through urine, mostly in conjugated form, while in feces, hormones are mainly excreted in free form. The main metabolites of norone and norandrostenediol in urine are 19-norandrosterone (19-NA).
Indications
The dermatology department is used for auxiliary treatment, which is caused by the negative Nitrogen balance caused by the use of large doses of corticosteroids, while increasing the protein in food; It is also used for exfoliative dermatitis, pemphigus, dermatomyositis, scleroderma, and senile skin pruritus. In addition, for patients with severe burns, malignant tumors before and after surgery, difficult healing after fractures, and severe osteoporosis, premature infants, significantly delayed growth and development, dwarfism, severe malnutrition, loss of appetite, chronic diarrhea, and other serious consumptive diseases, this product can be given in addition to other treatments. Breast cancer that is not suitable for surgery can alleviate symptoms, and functional uterine bleeding and uterine fibroids can be applied.
Function and purpose
It is a anabolic steroid. Its main function is to promote protein synthesis, inhibit protein decomposition, enable muscle growth, weight gain, and retain water, sodium, calcium, and phosphorus. Clinically, it is mainly used for cases of insufficient protein synthesis and increased breakdown, such as malnutrition, pediatric dysplasia, severe burns, postoperative recovery period, difficult fracture healing, osteoporosis in the elderly, and chronic consumptive diseases (such as chronic liver and kidney diseases, advanced malignant tumors, hyperthyroidism, and anemia); It is also used for negative Nitrogen balance caused by long-term massive use of glucocorticoid, but the protein composition in food should be increased at the same time. This product has a foul odor and is almost insoluble in water. It is easily soluble in ethanol and fatty oil.
Adverse reactions
There is a slight masculinization effect. Women may have hirsutism, acne, rough voice, clitoral hypertrophy, amenorrhea or menstrual disorders after use.