bmk pmk cas 79099-07-3 BDO
Tetracaine CAS 94-24-6 White powder 99% Local Anesthesia Drugs
Product Specification:
Product Name: | Tetracaine |
CAS No: | 94-24-6 |
Molecular Formular: | C15H24N2O2 |
Molecular Weight: | 264.36 |
EINECS No.: | 202-316-6 |
Melting point: | 41.0 to 45.0 °C |
Boiling point: | 407.59°C (rough estimate) |
Place of Origin: | China |
Type: | Pharmaceutical Intermediates |
Appearance: | Powder |
Color | White |
Purity: | 99.9% |
Packing: | 1kg,25kg or as per requirement |
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Mechanism of Action:
Tetracaine acts by blocking the nerve systems. It does this by blocking the sodium ion channels needed for the conduction and initiation of neural impulses, thereby affecting the local anesthesia. Tetracaine acts by altering the function of calcium release channels that controls the release of calcium frim intracellular cells.
Application:
Tetracaine topical (for the skin) is used to numb various body parts before a surgical procedure or a medical test. Conversely, tetracaine ophthalmic drops are used as local anesthetic for the eyes.
General Description:
Tetracaine was developed to address the low potency andshort duration of action of procaine and chloroprocaine. The addition of the butyl side chain on the para nitrogen increasesthe lipid solubility of the drug and enhances the topical potencyof tetracaine. The plasma half-life is 120 to 150 seconds.Topically applied tetracaine to unbroken skin requires 30 to 45minutes to confer topical anesthesia. Tetracaine 4% gel is superiorthan eutectic mixture with] (EMLA) (an emulsionof and prilocaine) in preventing pain associatedwith needle procedures in children. Tetracaine metabolism issimilar to procaine ester metabolism yielding parabutylaminobenzoicacid and dimethylaminoethanol and conjugatesexcreted in the urine. The pKa of the dimethylated nitrogen is8.4 and tetracaine is formulated as a hydrochloride salt with apH of 3.5 to 6.0. The increased absorption from topical siteshas resulted in reported toxicity.
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Product name | Benzocaine |
CAS NO | 94-09-7 |
Appearance | White powder |
Purity | ≥99% |
Items of analysis | Specification |
Identification | Consistent with the standard chart |
Reactive identification | Orange red |
Melting point | 88ºC-92ºC |
Less on drying | ≤0.5% |
Easy carbide | Comply with USP standards |
Residue on ignition | ≤0.1% |
Heavy metals | ≤10 ppm |
Total impurity | ≤1.0% |
Assay | 98-102% |
Grade | Pharma Grade |
Package | According to customers's requirements |