Product Name: Diethyl(phenylacetyl)malonate
English synonyms:Diethyl(phenylacetyl)malonate;Propanedioicacid,2-(2-phenylacetyl)-,1,3-diethylester;diethyl2-(2-phenylacetyl)propanedioate;diethyl2-(2-phenylacetylChemicalbook)propanedioatewickrbettyml;Cas20320-59-6;Propanedioicacid,(phenylacetyl)-,diethylester;PharmaceuticalintermediatesDiethyl(phenylacetyl)malonate;newp
Purity:99%
Chemical properties.
Diethyl phenyllevulmalonate contains two ester bonds, which are relatively low in reactivity, but can be hydrolyzed with appropriate catalysts to produce compounds such as phenylacetic acid and ethanol. The compound can also undergo ester Chemicalbook exchange reactions with other alcohols to produce different ester compounds. For example, methyl phenacemalonate can be obtained by reacting with methanol. Phenyllevulmalonic acid can be generated from the compound by acid-catalyzed hydrolysis reaction, and phenylacetic acid and diethyl malonate can be obtained by further adding water.
Application.
Diethyl phenyllevulmalonic acid contains two strong hydrophobic ethyl acetate groups in its molecular structure, so that it has a certain hydrophobicity, the compound is not easy to dissolve in water, but has good solubility in Chemicalbook organic solvents, such as ethanol, ether, benzene, etc. Diethyl phenyllevulmalonate is a kind of intermediate in organic synthesis, which is used to synthesize heterocyclic compounds in organic chemistry.
Production.
The anhydrous ethanol, which was co-steamed with diethyl phthalate and sodium metal, was added to the mixture of diethyl malonate, carbon tetrachloride and magnesium. The reaction was heated to start, and the temperature was controlled to smooth the reaction. Then add Chemicalbook anhydrous ether, heat for 1h, add the ether solution of phenacetochloride (add slowly, do not make the reaction too drastic). After the reaction, the oil layer was separated by cooling and water, and the ether was evaporated under pressure to obtain diethyl phenacetomalonate.
Office No# 383, 16192 Coastal Highway, Lewes, Delaware 19958, USA
